Dark matter is a bit past being just a placeholder now. We've been able to see some of its effects in clusters. We just can't interact with it. Dark Energy? Now that's the placeholder.
In this world, there is nothing as impartial as death. For all living creatures, death is sure to eventually come knocking. Death is an equalizer - it is an absolute truth - and it is always lingering right beside us. Nevertheless, people make the best use of their wits and courage.... struggling... floundering... they cling to life until the very end. You see, we actually like this unjust and unequal world...